Familial Multiple Endocrine Neoplasia Type 1 (MEN1)

Familial Multiple Endocrine Neoplasia Type 1 is an inherited disorder affecting the endocrine glands. The disorder affects both males and females equally. MEN1 is also sometimes called Wermer Syndrome.

People with MEN1 carry a gene which makes them prone to the development of pituitary tumours, parathyroid disease, tumours in the pancreas and occasionally tumours in the other endocrine glands. The parathyroids are the glands most often affected by MEN1 and the pituitary becomes overactive in about 1 in 6 persons. The cause of pitutary overactivity is usually a benign tumour called a prolactinoma.

A dedicated support group exists specifically for those with Multiple Endocrine Neoplasia. Visit the AMEND website at www.amend.org.uk