Tuesday, 07 February 2012

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Glossary

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Term Definition
Multiple Endocrine Neoplasia Type 1This is a rare inherited condition in which affected individuals tend to develop tumours of the pituitary gland.
NeurohypophysisAn alternative name for the posterior pituitary gland.
Non-functioning tumourA tumour which does not produce any of the pituitary hormones.
OctreotideA somatostatin analogue used to reduce levels of growth hormone.
OestrogenFemale sex hormone, which is produced by the ovaries.
OligomenorrhoeaAbnormally infrequent menstrual periods. Often the interval between periods exceeds 40 days.
Optic Nerve HypoplasiaRare congenital underdevelopment of the midline of the brain affecting sight, and sometimes producing hypopituitarism, diabetes insipidus, and possible failure of the adrenal and thyroid glands.
OsteoporosisThinning of the bones with increased risk of bone fracture. The condition is associated with deficiency of oestrogen or testosterone. Osteopenia is the term given to milder bone thinning, less severe than osteoporosis.
ParlodelThe brand name of bromocriptine.
Pituitary glandA gland, as small as a pea, located at the base of the brain. It produces hormones, which in turn control the hormone production of many other glands in the body.
Pituitary tumourA tumour, almost always non-cancerous, of the pituitary gland.
ProgesteroneFemale sex hormone, which is produced by the ovaries.
ProlactinA hormone often called the 'milk hormone' because its main function is to stimulate the breasts after childbirth. However, men also have prolactin, although the function of this hormone in males is not clear.
ProlactinomaA pituitary tumour which produces prolactin. This can be a microprolactinoma or macroprolactinoma.
RadiotherapyTreatment with X-rays.
Recombinant human GHSynthetically produced growth hormone, which has the same structure as natural human growth hormone.
SandostatinThe brand name of octreotide.
Septo Optic DysplasiaRare congenital underdevelopment of the midline of the brain affecting sight, and sometimes producing hypopituitarism, diabetes insipidus, and possible failure of the adrenal and thyroid glands.
Sex hormonesLuteinising hormone (LH) and follicle-stimulating hormone (FSH) are produced by the pituitary gland and stimulate the ovaries to produce oestrogen (in women) and testosterone (in men).
Short statureOften due to underproduction of growth hormone.
Sleep apnoeaA condition in which you stop breathing for a few moments while asleep. This causes poor quality sleep such that you wake in the morning with a headache and still feeling tired, and can result in you falling asleep during the day. The partners of sufferers typically complain they are bad snorers. Sleep apnoea is a common disorder in patients with acromegaly.
SomatostatinA naturally occurring hormone that reduces GH release from the pituitary gland. Man-made modified versions of somatostatin are known as somatostatin analogues.
SomatotrophinGrowth hormone.
Somatuline LAThe brand name of lanreotide.
Subcutaneous injectionAn injection under the skin, as opposed to deeper into the muscle.
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